Scripties UMCG - Rijksuniversiteit Groningen
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The incidence and management of neonatal hypoglycaemia in “healthy” neonates considered at risk

(2018) Berings, B. (Bodil)

Objectives Neonates at risk for hypoglycaemia are routinely screened, although it is unclear to what extent different risk factors influence the incidence of hypoglycaemia.
As part of the HypoNNL study, the goal of this study is to determine which group of neonates at risk develop hypoglycaemia, to be able to formulate a new national screening protocol. The main aim of this sub-study is to evaluate the incidence of hypoglycaemia in following sub-groups: birthweight <P2,3, P2,3-P5 and P5-P10.
Methods This is a retrospective study analysing neonates screened for neonatal hypoglycaemia at the DZ. Neonates were included when they fulfilled at least one of the inclusion criteria: (late) prematurity 35-37 weeks, small for gestational age (SGA) <P10, large for gestational age (LGA) >P90, maternal diabetes or maternal antihypertensive drugs. Neonates with congenital disorders or ill neonates were excluded.
Results 830 neonates were included, of which 187 (22,5%) developed hypoglycaemia. The incidence of hypoglycaemia was highest in the prematurity group (38,6%) and lowest in the group of maternal diabetes exclusively treated with a diet (13,5%). There was no significant difference in incidence in the SGA sub-groups.
Conclusions No difference was found in the SGA sub-groups. Until further evidence is found, all neonates <P10 should be screened for neonatal hypoglycaemia. As the incidence was lowest in cases of maternal diabetes exclusively treated with a diet, it should be reconsidered whether these neonates need to be screened.

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